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https://doi.org/10.12688/wellcomeopenres.14914.1
Research Note metrics
Exploring the context of diacidic motif DE as a signal for unconventional protein secretion in eukaryotic proteins
[version 1; peer review: 2 approved]
Sreedevi Padmanabhan, Malay Ranjan Biswal, Ravi Manjithaya, Meher K. Prakash
Peer Reviewers Vivek Malhotra; Suresh Subramani
  • Funders
  • Science and Engineering Research Board
  • DBT India Alliance
  • Jawaharlal Nehru Centre for Advanced Scientific Research
PUBLISHED 19 Nov 2018
https://doi.org/10.12688/wellcomeopenres.14674.2
Research Article metrics
Revised
Understanding the cultural meanings of stroke in the Ghanaian setting: A qualitative study exploring the perspectives of local community residents
[version 2; peer review: 2 approved]
Olutobi Sanuade
Peer Reviewers Gillian Lewando Hundt; Christopher McKevitt
  • Funder
  • Wellcome Trust
LATEST VERSION PUBLISHED 14 Nov 2018
https://doi.org/10.12688/wellcomeopenres.14073.3
Method Article metrics
Revised
ANIMA: Association network integration for multiscale analysis
[version 3; peer review: 2 approved, 1 approved with reservations]
Armin Deffur, Robert J. Wilkinson, Bongani M. Mayosi, Nicola M. Mulder
Peer Reviewers Christopher L. Plaisier; James A. Eddy; Emre Guney
  • Funders
  • Wellcome Trust
  • Francis Crick Institute
  • Hasso Plattner Foundation
  • Medical Research Council (South Africa)
  • Newton Fund
LATEST VERSION PUBLISHED 14 Nov 2018
https://doi.org/10.12688/wellcomeopenres.14924.1
Data Note metrics
Clinical Annotation Reference Templates: a resource for consistent variant annotation
[version 1; peer review: 1 approved with reservations, 1 not approved]
Shawn Yost, Márton Münz, Shazia Mahamdallie, Anthony Renwick, Elise Ruark, Nazneen Rahman
Peer Reviewers Marina T. DiStefano; Jeroen F J Laros, Mihai Lefter and Sander Bollen
  • Funder
  • Wellcome Trust
PUBLISHED 14 Nov 2018
https://doi.org/10.12688/wellcomeopenres.14911.1
Research Note metrics
xNgn2 induces expression of predominantly sensory neuron markers in Xenopus whole embryo ectoderm but induces mixed subtype expression in isolated ectoderm explants
[version 1; peer review: 2 approved with reservations]
Laura J.A. Hardwick, Anna Philpott
Peer Reviewers Eric J. Bellefroid, Simon Desiderio and Simon Vermeiren; Branko V. Latinkic
  • Funders
  • Wellcome Trust
  • Peterhouse
  • Medical Research Council
PUBLISHED 08 Nov 2018
https://doi.org/10.12688/wellcomeopenres.14587.2
Study Protocol metrics
Revised
Intrathecal Immunoglobulin for treatment of adult patients with tetanus: A randomized controlled 2x2 factorial trial
[version 2; peer review: 2 approved]
Huỳnh Thị Loan, Lam Minh Yen, Evelyne Kestelyn:, Nguyen Van Hao, Tran Tan Thanh, Nguyen Thi Phuong Dung, Hugo C. Turner, Ronald B. Geskus, Marcel Wolbers, Le Van Tan, H. Rogier Van Doorn, Nicholas P. Day, Duncan Wyncoll, Tran Tinh Hien, Guy E. Thwaites, Nguyen Van Vinh Chau, C. Louise Thwaites
Peer Reviewers Joanne M. Langley; Philip Bejon
  • Funder
  • Wellcome Trust
LATEST VERSION PUBLISHED 05 Nov 2018
https://doi.org/10.12688/wellcomeopenres.14870.1
Open Letter metrics
The Genetic Sphygmomanometer: an argument for routine genome-wide genotyping in the population and a new view on its use to inform clinical practice
[version 1; peer review: 3 approved, 1 approved with reservations]
Nicholas John Timpson, Frank Dudbridge
Peer Reviewers Nicholas G. Martin; David J. Porteous; Zoltan Kutalik; Dorret I. Boomsma and Brandon Johnson
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • National Institute for Health Research
PUBLISHED 31 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14754.2
Software Tool Article metrics
Revised
ICR142 Benchmarker: evaluating, optimising and benchmarking variant calling performance using the ICR142 NGS validation series
[version 2; peer review: 2 approved]
Elise Ruark, Esty Holt, Anthony Renwick, Márton Münz, Matthew N. Wakeling, Sian Ellard, Shazia Mahamdallie, Shawn Yost, Nazneen Rahman
Peer Reviewers Oliver Hofmann; Birgit Sikkema-Raddatz and Lennart F. Johansson
  • Funder
  • Wellcome Trust
LATEST VERSION PUBLISHED 31 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14692.3
Research Note metrics
Revised
Importance of human demographic history knowledge in genetic studies involving multi-ethnic cohorts
[version 3; peer review: 2 approved]
Benard W. Kulohoma
Peer Reviewers Michèle Ramsay; Nicola J. Mulder
  • Funders
  • Wellcome Trust
  • National Human Genome Research Institute
LATEST VERSION PUBLISHED 31 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14439.2
Research Article metrics
Revised
Ethical considerations in Controlled Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study in Kenya
[version 2; peer review: 2 approved]
Maureen Njue, Patricia Njuguna, Melissa C. Kapulu, Gladys Sanga, Philip Bejon, Vicki Marsh, Sassy Molyneux, Dorcas Kamuya
Peer Reviewers Christine Grady; Danielle I. Stanisic
  • Funders
  • Wellcome Trust
  • Global Health Bioethics Network and the Wellcome Centre for Ethics and Humanities
LATEST VERSION PUBLISHED 29 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14882.1
Systematic Review metrics
Health risk behavior among perinatally HIV exposed uninfected adolescents: A systematic review
[version 1; peer review: 2 approved with reservations]
Derrick Ssewanyana, Patrick N Mwangala, Moses Kachama Nyongesa, Anneloes van Baar, Charles R Newton, Amina Abubakar
Peer Reviewers Farhad Shokraneh; Arvin Bhana
  • Funders
  • Wellcome Trust
  • Department for International Development, UK Government
  • Medical Research Council
PUBLISHED 29 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14645.4
Research Article metrics
Revised
Probing Plasmodium falciparum sexual commitment at the single-cell level
[version 4; peer review: 2 approved]
Nicolas M.B. Brancucci, Mariana De Niz, Timothy J. Straub, Deepali Ravel, Lauriane Sollelis, Bruce W. Birren, Till S. Voss, Daniel E. Neafsey, Matthias Marti
Peer Reviewers Lyn-Marie Birkholtz, Riette van Biljon and Roelof van Wyk; Björn F.C. Kafsack and Asaf Poran
  • Funders
  • Wellcome Trust
  • Royal Society
  • National Institute of Allergy and Infectious Diseases
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
  • EMBO
  • Burroughs Wellcome Fund
LATEST VERSION PUBLISHED 17 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14493.2
Research Article metrics
Revised
Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse
[version 2; peer review: 2 approved]
Chiara Beilin, Kaushik Choudhuri, Gerben Bouma, Dessislava Malinova, Jaime Llodra, David L. Stokes, Motumu Shimaoka, Timothy A. Springer, Michael L. Dustin, Adrian J. Thrasher, Siobhan O. Burns
Peer Reviewers Matthew Collin; Jung-Hyun Park and Tae-Hyoun Kim
  • Funders
  • Wellcome Trust
  • Primary Immunodeficiency Association
  • Child Health Research Appeal Trust
  • European Union
  • ICH Biomedical Research Centre
  • Bogue Research Fellowship
  • National Institutes of Health
  • Cancer Research Institute
LATEST VERSION PUBLISHED 17 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14666.2
Research Note metrics
Revised
Ophthalmic signs in Ugandan adults with HIV-associated cryptococcal meningitis: A nested analysis of the ASTRO-CM cohort
[version 2; peer review: 2 approved]
Rachel R Atherton, Jayne P. Ellis, Fiona V Cresswell, Joshua Rhein, David R. Boulware
Peer Reviewers Mosepele Mosepele; Héctor Pérez and Emilio Dodds
  • Funders
  • Wellcome Trust
  • National Institute of Neurological Disorders and Stroke
  • National Institute of Allergy and Infectious Diseases
  • Department for International Development, UK Government
  • Medical Research Council
  • Fogarty International Center
LATEST VERSION PUBLISHED 12 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14069.2
Research Article metrics
Revised
Classification and characterisation of brain network changes in chronic back pain: A multicenter study
[version 2; peer review: 3 approved]
Hiroaki Mano, Gopal Kotecha, Kenji Leibnitz, Takashi Matsubara, Christian Sprenger, Aya Nakae, Nicholas Shenker, Masahiko Shibata, Valerie Voon, Wako Yoshida, Michael Lee, Toshio Yanagida, Mitsuo Kawato, Maria Joao Rosa, Ben Seymour
Peer Reviewers Apkar Vania Apkarian; Tor D. Wager; Jiro Kurata
  • Funders
  • Wellcome Trust
  • National Institute for Information and Communications Technology
  • Japan Agency for Medical Research and Development
  • Ministry of Education, Culture, Sports, Science and Technology
  • Arthritis Research UK
  • University of Cambridge
  • Japan Society for the Promotion of Science
LATEST VERSION PUBLISHED 10 Oct 2018
https://doi.org/10.12688/wellcomeopenres.12237.2
Research Article metrics
Revised
The integration site of the APP transgene in the J20 mouse model of Alzheimer’s disease
[version 2; peer review: 2 approved, 1 approved with reservations]
Justin L. Tosh, Matthew Rickman, Ellie Rhymes, Frances E. Norona, Emma Clayton, Lennart Mucke, Adrian M. Isaacs, Elizabeth M.C. Fisher, Frances K. Wiseman
Peer Reviewers Karen H. Ashe; Takaomi C. Saido; Guillaume Pavlovic
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Alzheimer's Society
  • Alzheimer’s Research UK
LATEST VERSION PUBLISHED 10 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14847.1
Research Article metrics
Using machine learning to guide targeted and locally-tailored empiric antibiotic prescribing in a children's hospital in Cambodia
[version 1; peer review: 2 approved]
Mathupanee Oonsivilai, Yin Mo, Nantasit Luangasanatip, Yoel Lubell, Thyl Miliya, Pisey Tan, Lorn Loeuk, Paul Turner, Ben S. Cooper
Peer Reviewers Quentin Leclerc and Gwen Knight; Randall C Wetzel and Melissa Aczon
  • Funders
  • Wellcome Trust
  • Department for International Development
  • Medical Research Council
  • Singapore National Medical Research Council
PUBLISHED 10 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14848.1
Research Note metrics
Interaction between opposing modes of phospho-regulation of the proneural proteins Ascl1 and Ngn2
[version 1; peer review: 2 approved]
Laura J.A. Hardwick, Anna Philpott
Peer Reviewers Karel Dorey; Kristine A. Henningfeld
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Peterhouse Research Fellowship
PUBLISHED 01 Oct 2018
https://doi.org/10.12688/wellcomeopenres.14713.2
Research Article metrics
Revised
Proposed classification for interproximal contacts of primary molars using CBCT: a pilot study
[version 2; peer review: 2 approved]
M. Kirthiga, M. S. Muthu, G. Kayalvizhi, C. Krithika
Peer Reviewers Sivakumar Nuvvula; Manikandan Ekambaram
  • Funder
  • DBT India Alliance
LATEST VERSION PUBLISHED 27 Sep 2018
https://doi.org/10.12688/wellcomeopenres.14552.2
Research Article metrics
Revised
A descriptive study of potential participant preferences for the design of an incentivised weight loss programme for people with type 2 diabetes mellitus attending a public hospital in Lima, Peru
[version 2; peer review: 2 approved]
Harold Akehurst, M. Amalia Pesantes, S. del Pilar Cornejo, Katty Manrique, Maria Lazo-Porras, Jill Portocarrero, Francisco Diez-Canseco, Antonio Bernabe-Ortiz, Antonio J. Trujillo, J. Jaime Miranda
Peer Reviewers Luzia Valentini and Sara Ramminger; Ramfis Nieto-Martínez
  • Funders
  • Wellcome Trust
  • National Heart, Lung, and Blood Institute
  • World Diabetes Foundation
  • Alliance for Health Policy and Systems Research
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
  • Department for International Development
  • International Development Research Center Canada
  • Medical Research Council
  • Fogarty International Center
  • National Cancer Institute
  • Inter-American Institute for Global Change Research
  • National Institute of Mental Health
LATEST VERSION PUBLISHED 27 Sep 2018
1,821-1,840 of 2,072 ARTICLES
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