The Francis Crick Institute
The Francis Crick Institute
Immunology Interest Group
Research Article
metrics
Revised
Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Oscar Della Pasqua;
Jotam Pasipanodya;
Fajri Gafar
- Funders
- Wellcome Trust
- NRF
- Francis Crick Institute
- South African Medical Research Council through its TB and HIV Collaborating Centres Programme with funds received from the National Department of Health
- National Institutes of Health
- EDCTP
- South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation (NRF) of South Africa
Research Article
metrics
Revised
Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
[version 2; peer review: 2 approved]
Peer Reviewers
Leonie Taams;
Christopher A Hunter
- Funders
- Cancer Research UK
- Wellcome
- Medical Research Council
Research Note
metrics
Revised
Estimating the epidemiology of chronic Hepatitis B Virus (HBV) infection in the UK: what do we know and what are we missing?
[version 2; peer review: 3 approved]
Peer Reviewers
Lung-Yi Mak;
Jonggi Choi;
Anders Boyd
- Funder
- Wellcome Trust
Review
metrics
Revised
Sexual Dimorphism in Chronic Hepatitis B Virus (HBV) Infection: Evidence to Inform Elimination Efforts
[version 3; peer review: 2 approved]
Peer Reviewers
Yuchen Xia;
Andri Rauch
- Funders
- Wellcome Trust
- Cancer Research UK
- Wellcome
- Medical Research Council
- National Institutes of Health
Research Article
metrics
Symptom profiles and accuracy of clinical case definitions for COVID-19 in a community cohort: results from the Virus Watch study
[version 1; peer review: 2 approved]
Peer Reviewers
Benjamin J. Cowling;
Michael E DeWitt
- Funders
- Wellcome Trust
- Medical Research Council
Research Article
metrics
Revised
10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity
[version 3; peer review: 2 approved]
Peer Reviewers
Rodrigo M Corder;
Rhea J Longley
- Funders
- Wellcome Trust
- Francis Crick Institute
- Medical Research Council
Research Article
metrics
Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon
[version 1; peer review: 2 approved]
Peer Reviewers
James Davis;
Joseph Fauver
- Funders
- Wellcome Trust
- Medical Research Council
- Genome Research Limited
- National Institute of Health Research
Research Article
metrics
Revised
Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating
[version 2; peer review: 2 approved]
Peer Reviewers
Gert U. van Zyl;
Xuan Xue
- Funders
- Wellcome Trust
- Invisismart Technologies
Study Protocol
metrics
Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis [LASER-TBM]
[version 1; peer review: 2 approved]
Peer Reviewers
Julie Huynh;
Frederic Ello
- Funders
- Wellcome Trust
- European and Developing Countries Clinical Trials Partnership
- Cancer Research UK
- Meningitis Now
- Medical Research Council
- National Institutes of Health
- National Research Foundation
- UK Research and Innovation
Method Article
metrics
Revised
SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay
[version 2; peer review: 2 approved]
Peer Reviewers
Michael Knop and Viet Loan Dao Thi;
Vanessa Revindran-Stam and Leyi Wang
- Funders
- Wellcome Trust
- European Molecular Biology Organization
- The John Black Charitable Foundation
- Cancer Research UK
- Rosetrees Trust
- Medical Research Council
- H2020 Marie Skłodowska-Curie Actions
Study Protocol
metrics
Revised
The diagnosis of tuberculous meningitis in adults and adolescents: protocol for a systematic review and individual patient data meta-analysis to inform a multivariable prediction model
[version 3; peer review: 2 approved]
Peer Reviewers
Ravindra Kumar Garg;
Kym I.E. Snell
- Funder
- Wellcome Trust
Research Article
metrics
Revised
Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease
[version 2; peer review: 2 approved]
Peer Reviewers
Asma Farhat, Mariem Radhouani and Sylvia Knapp;
Padraic Fallon
- Funders
- Wellcome Trust
- Asthma UK
- Cancer Research UK
- Medical Research Council
Research Article
metrics
C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo
[version 1; peer review: 2 approved]
Peer Reviewers
Peter Staeheli;
Igor Kramnik
- Funders
- Wellcome Trust
- Cancer Research UK
- Burroughs Wellcome Fund
- National Institute of Health
- UK Medical Research Council
- Boehringer Ingelheim Fonds
Research Article
metrics
Variation in pre-therapy levels of selected Mycobacterium tuberculosis transcripts in sputum and their relationship with 2-month culture conversion
[version 1; peer review: 2 approved with reservations]
Peer Reviewers
Michelle B. Ryndak;
Kalpana Sriraman and Nerges Mistry
- Funders
- Wellcome Trust
- Medical Research Council
- Cancer Research UK
- FP7 People: Marie-Curie Actions
- Seventh Framework Programme
- National Research Foundation
Research Note
metrics
Revised
Antigenicity of peptides comprising the immunosuppressive domain of the retroviral envelope glycoprotein
[version 2; peer review: 2 approved]
Peer Reviewers
Jean-Marie Saint-Remy;
Stephanie Gras and Emma Grant
- Funders
- Wellcome Trust
- Francis Crick Institute
- Cancer Research UK
- Medical Research Council