The Francis Crick Institute
The Francis Crick Institute
Research Article
metrics
Revised
Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid
[version 2; peer review: 2 approved]
Peer Reviewers
Luis Larrondo;
Xiaodong Zhuang
- Funders
- Wellcome Trust
- Royal Society
Research Article
metrics
Revised
Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating
[version 2; peer review: 2 approved]
Peer Reviewers
Gert U. van Zyl;
Xuan Xue
- Funders
- Wellcome Trust
- Invisismart Technologies
Software Tool Article
metrics
Ultraplex: A rapid, flexible, all-in-one fastq demultiplexer
[version 1; peer review: 2 approved]
Peer Reviewers
Matteo Cereda;
Grzegorz Kudla
- Funders
- Wellcome Trust
- Cancer Research UK
- Francis Crick Institute
- Okinawa Institute of Science and Technology Graduate University
- Medical Research Council
Study Protocol
metrics
Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis [LASER-TBM]
[version 1; peer review: 2 approved]
Peer Reviewers
Julie Huynh;
Frederic Ello
- Funders
- Wellcome Trust
- European and Developing Countries Clinical Trials Partnership
- Cancer Research UK
- Meningitis Now
- Medical Research Council
- National Institutes of Health
- National Research Foundation
- UK Research and Innovation
Software Tool Article
metrics
Mixology: a tool for calculating required masses and volumes for laboratory solutions
[version 1; peer review: 2 approved]
Peer Reviewers
Joachim Goedhart;
Pablo Cárdenas
- Funder
- Wellcome Trust
Method Article
metrics
Revised
SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay
[version 2; peer review: 2 approved]
Peer Reviewers
Michael Knop and Viet Loan Dao Thi;
Vanessa Revindran-Stam and Leyi Wang
- Funders
- Wellcome Trust
- European Molecular Biology Organization
- The John Black Charitable Foundation
- Cancer Research UK
- Rosetrees Trust
- Medical Research Council
- H2020 Marie Skłodowska-Curie Actions
Study Protocol
metrics
Revised
The diagnosis of tuberculous meningitis in adults and adolescents: protocol for a systematic review and individual patient data meta-analysis to inform a multivariable prediction model
[version 3; peer review: 2 approved]
Peer Reviewers
Ravindra Kumar Garg;
Kym I.E. Snell
- Funder
- Wellcome Trust
Research Article
metrics
Revised
Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease
[version 2; peer review: 2 approved]
Peer Reviewers
Asma Farhat, Mariem Radhouani and Sylvia Knapp;
Padraic Fallon
- Funders
- Wellcome Trust
- Asthma UK
- Cancer Research UK
- Medical Research Council
Method Article
metrics
Revised
Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets
[version 2; peer review: 2 approved]
Peer Reviewers
Andrew G. Stephen;
Nicolas Bery
- Funders
- Wellcome Trust
- Cancer Research UK
- European Research Council
- Medical Research Council
Research Article
metrics
Revised
Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.
[version 2; peer review: 2 approved]
Peer Reviewers
Uwe Knippschild;
Patrick A. Eyers
- Funders
- Wellcome Trust
- Medical Research Council
Research Article
metrics
C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo
[version 1; peer review: 2 approved]
Peer Reviewers
Peter Staeheli;
Igor Kramnik
- Funders
- Wellcome Trust
- Cancer Research UK
- Burroughs Wellcome Fund
- National Institute of Health
- UK Medical Research Council
- Boehringer Ingelheim Fonds
Research Article
metrics
Variation in pre-therapy levels of selected Mycobacterium tuberculosis transcripts in sputum and their relationship with 2-month culture conversion
[version 1; peer review: 2 approved with reservations]
Peer Reviewers
Michelle B. Ryndak;
Kalpana Sriraman and Nerges Mistry
- Funders
- Wellcome Trust
- Medical Research Council
- Cancer Research UK
- FP7 People: Marie-Curie Actions
- Seventh Framework Programme
- National Research Foundation
Research Article
metrics
Revised
Genomic and transcriptomic comparisons of closely related malaria parasites differing in virulence and sequestration pattern
[version 2; peer review: 2 approved]
Peer Reviewers
Xin-zhuan Su;
Matthew L. Aardema
- Funders
- Wellcome Trust
- Cancer Research UK
- Medical Research Council
Method Article
metrics
Revised
ANIMA: Association network integration for multiscale analysis
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Christopher L. Plaisier;
James A. Eddy;
Emre Guney
- Funders
- Wellcome Trust
- Francis Crick Institute
- Hasso Plattner Foundation
- Medical Research Council (South Africa)
- Newton Fund
Research Note
metrics
‘Read–through marking’ reveals differential nucleotide composition of read-through and truncated cDNAs in iCLIP
[version 1; peer review: 4 approved]
Peer Reviewers
Sander Granneman;
Donald Rio and Qingqing Wang;
Jeremy R. Sanford, Andrew Wallace and Julia Philipp;
Grzegorz Kudla
- Funders
- Wellcome Trust
- European Research Council
Research Article
metrics
Revised
1H-NMR as implemented in several origin of life studies artificially implies the absence of metabolism-like non-enzymatic reactions by being signal-suppressed
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers
Christian Ludwig and Thomas Brendan Smith;
Amy A. Caudy
- Funders
- Wellcome Trust
- European Research Council
Research Article
metrics
Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo
[version 1; peer review: 2 approved, 2 approved with reservations]
Peer Reviewers
Timothy J.A. Chico;
Dong Liu;
Nicola Facchinello;
Thomas A. Hawkins
- Funders
- Wellcome Trust
- Cancer Research UK
- Fondation Leducq
- Medical Research Council
Research Article
metrics
Revised
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
[version 2; peer review: 3 approved]
Peer Reviewers
David Brook;
Nadia Rosenthal and Steve Murray;
Lydia Teboul
- Funders
- Wellcome Trust
- Cancer Research UK
- Medical Research Council
Research Note
metrics
Revised
Antigenicity of peptides comprising the immunosuppressive domain of the retroviral envelope glycoprotein
[version 2; peer review: 2 approved]
Peer Reviewers
Jean-Marie Saint-Remy;
Stephanie Gras and Emma Grant
- Funders
- Wellcome Trust
- Francis Crick Institute
- Cancer Research UK
- Medical Research Council
Method Article
metrics
ultraLM and miniLM: Locator tools for smart tracking of fluorescent cells in correlative light and electron microscopy
[version 1; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers
Eija Jokitalo and Ilya Belevich;
Harald F. Hess;
Rainer Kaufmann;
Thomas H. Sharp and Maarten Tuijtel
- Funders
- Wellcome Trust
- Cancer Research UK
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
- Engineering and Physical Sciences Research Council