The Francis Crick Institute

The Francis Crick Institute

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1-20 of 40 ARTICLES
https://doi.org/10.12688/wellcomeopenres.26466.1
Study Protocol metrics
What is the impact of metabolic dysfunction-associated steatotic liver disease (MASLD) on outcomes in people living with chronic hepatitis B (CHB)? An umbrella review protocol
[version 1; peer review: 1 approved with reservations]
Peer Reviewers Yoscelina E. Martinez-Lopez
  • Funders
  • Wellcome Trust
  • Francis Crick Institute
PUBLISHED 14 May 2026
https://doi.org/10.12688/wellcomeopenres.24390.1
Research Article metrics
Examining the association of live virus neutralisation activity of capillary microsamples and risk of SARS-CoV-2 infections: a nested case control study within the Virus Watch community cohort
[version 1; peer review: 1 approved]
Peer Reviewers Charles Sande
  • Funders
  • Wellcome Trust
  • MRC
PUBLISHED 24 Apr 2026
https://doi.org/10.12688/wellcomeopenres.25201.1
Research Article metrics
Activation of the aryl hydrocarbon receptor in mature adipocytes does not impact diet-induced obesity in mice
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Josephine Robb; Emiel van der Vorst
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Fondation Acteria
PUBLISHED 16 Feb 2026
https://doi.org/10.12688/wellcomeopenres.25134.1
Study Protocol metrics
Viral hepatitis and liver disease in the Mongolian community in London ('MoLo'): A mixed methods study protocol to investigate the epidemiology and burden of disease to inform clinical and public health interventions
[version 1; peer review: 1 approved]
Peer Reviewers Anders Boyd
  • Funders
  • Wellcome Trust
  • National Institute for Health and Care Research University College London Hospital Biomedical Research Centre
  • Hospital For Tropical Diseases Charity Funding, London
PUBLISHED 23 Jan 2026
https://doi.org/10.12688/wellcomeopenres.16890.2
Research Article metrics
Revised
Trends of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody prevalence in selected regions across Ghana
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Charles Sande; Kirsten E Wiens
  • Funders
  • Wellcome Trust
  • Francis Crick Institute
  • World Bank
  • National Institute for Health Research
LATEST VERSION PUBLISHED 15 Jan 2026
https://doi.org/10.12688/wellcomeopenres.23515.3
Research Article metrics
Revised
Drosophila AHR limits tumor growth and stem cell proliferation in the intestine
[version 3; peer review: 4 approved]
Peer Reviewers Julia B. Cordero; Jin Jiang and Mengjie Li; Ben Ohlstein; Palmira Barreira-Silva
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • Francis Crick Institute
  • Medical Research Council
LATEST VERSION PUBLISHED 25 Apr 2025
https://doi.org/10.12688/wellcomeopenres.23009.2
Research Article metrics
Revised
Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa
[version 2; peer review: 2 approved, 1 approved with reservations, 1 not approved]
Peer Reviewers Emilio Di Maria; Hermina Jakupović; Alexander J Mentzer and Amanda Chong; Maik Pietzner
  • Funders
  • Wellcome Trust
  • National Health and Medical Research Council
  • NIH
  • Gates Foundation
  • South Africa Medical Research Council
  • UK Research and Innovation
LATEST VERSION PUBLISHED 13 Jan 2025
https://doi.org/10.12688/wellcomeopenres.21000.1
Software Tool Article metrics
Riboseq-flow: A streamlined, reliable pipeline for ribosome profiling data analysis and quality control
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Can Cenik and Dayea Park; Shintaro Iwasaki and Kotaro Tomruro; Pavel Baranov and Jack Tierney
  • Funders
  • Wellcome Trust
  • Medical Research Council
PUBLISHED 11 Apr 2024
https://doi.org/10.12688/wellcomeopenres.20766.1
Software Tool Article metrics
A web tool for exploring the usage of medicines in hospitals in England
[version 1; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Kishore Kumar Jagadeesan; Fergus Hamilton; Brian Mackenna
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • Medical Research Council
PUBLISHED 19 Mar 2024
https://doi.org/10.12688/wellcomeopenres.17660.3
Research Article metrics
Revised
Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Oscar Della Pasqua; Jotam Pasipanodya; Fajri Gafar
  • Funders
  • Wellcome Trust
  • NRF
  • Francis Crick Institute
  • South African Medical Research Council through its TB and HIV Collaborating Centres Programme with funds received from the National Department of Health
  • National Institutes of Health
  • EDCTP
  • South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation (NRF) of South Africa
LATEST VERSION PUBLISHED 01 Mar 2024
https://doi.org/10.12688/wellcomeopenres.19680.2
Research Article metrics
Revised
Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
[version 2; peer review: 2 approved]
Peer Reviewers Leonie Taams; Christopher A Hunter
  • Funders
  • Cancer Research UK
  • Wellcome
  • Medical Research Council
LATEST VERSION PUBLISHED 01 Dec 2023
https://doi.org/10.12688/wellcomeopenres.19617.1
Research Article metrics
Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress
[version 1; peer review: 3 approved]
Peer Reviewers Roberto Bellelli; Karim Labib; Tim Humphrey
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • Worldwide Cancer Research
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 26 Jul 2023
https://doi.org/10.12688/wellcomeopenres.19453.1
Software Tool Article metrics
nf-core/clipseq - a robust Nextflow pipeline for comprehensive CLIP data analysis
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Yucheng Yang; Shiyong Liu; Emmanouil Maragkakis
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • Medical Research Council
  • Academy of Medical Sciences
PUBLISHED 04 Jul 2023
https://doi.org/10.12688/wellcomeopenres.18313.3
Software Tool Article metrics
Revised
Automated staging of zebrafish embryos using machine learning
[version 3; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Steffen Scholpp; Amin Allalou; Christian Tischer, Arif Khan and Sebastian Gonzalez-Tirado
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • Medical Research Council
LATEST VERSION PUBLISHED 26 Apr 2023
https://doi.org/10.12688/wellcomeopenres.17941.2
Research Note metrics
Revised
Estimating the epidemiology of chronic Hepatitis B Virus (HBV) infection in the UK: what do we know and what are we missing?
[version 2; peer review: 3 approved]
Peer Reviewers Lung-Yi Mak; Jonggi Choi; Anders Boyd
  • Funder
  • Wellcome Trust
LATEST VERSION PUBLISHED 09 Mar 2023
https://doi.org/10.12688/wellcomeopenres.17601.3
Review metrics
Revised
Sexual Dimorphism in Chronic Hepatitis B Virus (HBV) Infection: Evidence to Inform Elimination Efforts
[version 3; peer review: 2 approved]
Peer Reviewers Yuchen Xia; Andri Rauch
  • Funders
  • Wellcome Trust
  • Cancer Research UK
  • Wellcome
  • Medical Research Council
  • National Institutes of Health
LATEST VERSION PUBLISHED 11 May 2022
https://doi.org/10.12688/wellcomeopenres.17124.2
Research Article metrics
Revised
Quantification of fetal organ sparing in maternal low-protein dietary models
[version 2; peer review: 2 approved]
Peer Reviewers David J. Hill; Paula N. Gonzalez
  • Funders
  • Wellcome Trust
  • MRC National Institute for Medical Research
LATEST VERSION PUBLISHED 04 May 2022
https://doi.org/10.12688/wellcomeopenres.17479.1
Research Article metrics
Symptom profiles and accuracy of clinical case definitions for COVID-19 in a community cohort: results from the Virus Watch study
[version 1; peer review: 2 approved]
Peer Reviewers Benjamin J. Cowling; Michael E DeWitt
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Facebook
PUBLISHED 10 Mar 2022
https://doi.org/10.12688/wellcomeopenres.16562.3
Research Article metrics
Revised
10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity
[version 3; peer review: 2 approved]
Peer Reviewers Rodrigo M Corder; Rhea J Longley
  • Funders
  • Wellcome Trust
  • Francis Crick Institute
  • Medical Research Council
LATEST VERSION PUBLISHED 04 Feb 2022
https://doi.org/10.12688/wellcomeopenres.17295.1
Research Article metrics
Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon
[version 1; peer review: 2 approved]
Peer Reviewers James Davis; Joseph Fauver
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Genome Research Limited
  • National Institute of Health Research
PUBLISHED 10 Nov 2021
1-20 of 40 ARTICLES
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