Discovery Research Platform for Infection
Discovery Research Platform for Infection
Study Protocol
metrics
AWAITING PEER REVIEW
Characteristics and HIV-related Engagement of Male Sexual Partners of Female Sex Workers in Sub-Saharan Africa (SSA): a Scoping Review Protocol
[version 1; peer review: awaiting peer review]
Peer Reviewers
Invited
- Funder
- Wellcome Trust
Study Protocol
metrics
Efficacy and Safety of Long-acting Injectable Cabotegravir and Rilpivirine in Improving HIV-1 Control in sub-Saharan Africa: Protocol for a Phase 3b Open-Label Randomized Controlled Trial (IMPALA)
[version 1; peer review: 2 approved]
Peer Reviewers
Eisuke Adachi;
Stefano Rusconi
- Funder
- Janssen Pharmaceutica NV, a company of Johnson & Johnson
Research Article
metrics
Revised
Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa
[version 2; peer review: 2 approved, 1 approved with reservations, 1 not approved]
Peer Reviewers
Emilio Di Maria;
Hermina Jakupović;
Alexander J Mentzer and Amanda Chong;
Maik Pietzner
- Funders
- Wellcome Trust
- National Health and Medical Research Council
- NIH
- Gates Foundation
- South Africa Medical Research Council
- UK Research and Innovation
Research Article
metrics
Revised
Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Oscar Della Pasqua;
Jotam Pasipanodya;
Fajri Gafar
- Funders
- Wellcome Trust
- NRF
- Francis Crick Institute
- South African Medical Research Council through its TB and HIV Collaborating Centres Programme with funds received from the National Department of Health
- National Institutes of Health
- EDCTP
- South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation (NRF) of South Africa
Research Article
metrics
Revised
A multi-parameter diagnostic clinical decision tree for the rapid diagnosis of tuberculosis in HIV-positive patients presenting to an emergency centre
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Jim Connoly;
Maria Teresa Giordani;
Peter MacPherson
- Funders
- Wellcome Trust
- South African Medical Research Council
- National Research Foundation
Review
metrics
Peer Reviewers
Fabrice Bonnet;
Vishwanath Venketaraman
- Funders
- Wellcome Trust
- Cancer Research UK
- Francis Crick Institute
- Medical Research Council
- Meningitis Now
- National Institutes of Health
- UK Research and Innovation
Study Protocol
metrics
Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis [LASER-TBM]
[version 1; peer review: 2 approved]
Peer Reviewers
Julie Huynh;
Frederic Ello
- Funders
- Wellcome Trust
- European and Developing Countries Clinical Trials Partnership
- Cancer Research UK
- Meningitis Now
- Medical Research Council
- National Institutes of Health
- National Research Foundation
- UK Research and Innovation
Study Protocol
metrics
AntiRetroviral Therapy In Second-line: investigating Tenofovir-lamivudine-dolutegravir (ARTIST): protocol for a randomised controlled trial
[version 1; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Stephen Ian Walimbwa;
Laura Waters;
Loice Achieng Ombajo
- Funders
- Wellcome Trust
- Médecins Sans Frontières
- Department of Science and Technology, Republic of South Africa
- National Research Foundation
Review
metrics
Revised
Recent Developments in Tuberculous Meningitis Pathogenesis and Diagnostics
[version 3; peer review: 3 approved]
Peer Reviewers
James E. Scriven;
Joseph Zunt;
Michael J. Griffiths
- Funders
- Wellcome Trust
- National Institute of Neurological Disorders and Stroke
- European and Developing Countries Clinical Trials Partnership
- Cancer Research UK
- Meningitis Now
- National Research Foundation of South Africa
Open Letter
metrics
Before the whistle blows: developing new paradigms in tuberculosis screening to maximise benefit and minimise harm
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers
Daniel Gemechu Datiko;
Nargiza Parpieva and Laziz Turaev
- Funder
- Wellcome Trust
Study Protocol
metrics
Standard versus double dose dolutegravir in patients with HIV-associated tuberculosis: a phase 2 non-comparative randomised controlled (RADIANT-TB) trial
[version 1; peer review: 2 approved]
Peer Reviewers
Derek J. Sloan;
Kelly Dooley
- Funders
- Wellcome Trust
- Wellcome Trust - Wellcome Centre for Infectious Diseases Research in Africa
Study Protocol
metrics
Revised
The diagnosis of tuberculous meningitis in adults and adolescents: protocol for a systematic review and individual patient data meta-analysis to inform a multivariable prediction model
[version 3; peer review: 2 approved]
Peer Reviewers
Ravindra Kumar Garg;
Kym I.E. Snell
- Funder
- Wellcome Trust
Open Letter
metrics
Revised
Standardized approaches for clinical sampling and endpoint ascertainment in tuberculous meningitis studies
[version 2; peer review: 2 approved]
Peer Reviewers
William P. Howlett;
Benedict D. Michael
- Funders
- Wellcome Trust
- Cancer Research UK
- Meningitis Now
- Fogarty International Center of the National Institutes of Health
- European & Developing Countries Clinical Trials Partnership
- UK Medical Research Council
- National Institutes of Health
Open Letter
metrics
Revised
Management of intracranial tuberculous mass lesions: how long should we treat for?
[version 3; peer review: 3 approved]
Peer Reviewers
Jerome H. Chin;
Benedict Michael;
Julie Higashi
- Funders
- Wellcome Trust
- National Research Foundation SARChI Chair in Clinical Neurosciences
- Fogarty International Center
- National Institutes of Health
- South African Medical Research Council
- Department of Science and Technology, Republic of South Africa
- National Research Foundation, South Africa
Open Letter
metrics
Knowledge gaps and research priorities in tuberculous meningitis
[version 1; peer review: 3 approved]
Peer Reviewers
Christopher Vinnard;
Jamie Rylance;
Hardeep Singh Malhotra
- Funders
- Wellcome Trust
- European and Developing Countries Clinical Trials Partnership
- Cancer Research UK
- Francis Crick Institute
- Department for International Development, UK Government
- Meningitis Now
- Medical Research Council
- National Research Foundation
- UK Research and Innovation
Review
metrics
Neurocognitive and functional impairment in adult and paediatric tuberculous meningitis
[version 1; peer review: 2 approved]
Peer Reviewers
Reuben Robbins;
Monica Marta
- Funders
- Wellcome Trust
- Cancer Research UK
- Meningitis Now
- National Research Foundation of South Africa
- National Institutes of Health
- Newton Fund
Research Article
metrics
Variation in pre-therapy levels of selected Mycobacterium tuberculosis transcripts in sputum and their relationship with 2-month culture conversion
[version 1; peer review: 2 approved with reservations]
Peer Reviewers
Michelle B. Ryndak;
Kalpana Sriraman and Nerges Mistry
- Funders
- Wellcome Trust
- Medical Research Council
- Cancer Research UK
- FP7 People: Marie-Curie Actions
- Seventh Framework Programme
- National Research Foundation
Method Article
metrics
Revised
ANIMA: Association network integration for multiscale analysis
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Christopher L. Plaisier;
James A. Eddy;
Emre Guney
- Funders
- Wellcome Trust
- Francis Crick Institute
- Hasso Plattner Foundation
- Medical Research Council (South Africa)
- Newton Fund