Generation Scotland

Generation Scotland

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1-17 of 17 ARTICLES
 in 
https://doi.org/10.12688/wellcomeopenres.24955.1
Research Article metrics
Methodological Considerations When Using Polygenic Scores to Explore Parent-Offspring Genetic Nurturing Effects
[version 1; peer review: 2 approved with reservations]
Melisa Chuong, Alex S F Kwong, Carmen Amador, Chris S Haley, Andrew M McIntosh, Mark J Adams
Peer Reviewers Victória Trindade Pons; robert plomin
  • Funder
  • Wellcome Trust
PUBLISHED 06 Jan 2026
https://doi.org/10.12688/wellcomeopenres.17252.2
Data Note metrics
Revised
TeenCovidLife: a resource to understand the impact of the COVID-19 pandemic on adolescents in Scotland
[version 2; peer review: 2 approved]
Charlotte F Huggins, Chloe Fawns-Ritchie, Drew M Altschul, Archie Campbell, Clifford Nangle, Rebecca Dawson, Rachel Edwards, Robin Flaig, Louise Hartley, Christie Levein, Daniel L McCartney, Stephanie L Sinclair, Clare Dolan, Dawn Haughton, Judith Mabelis, Judith Brown, Jo Inchley, Daniel J Smith, Ian J Deary, Caroline Hayward, Riccardo E Marioni, Andrew M McIntosh, Cathie Sudlow, David J Porteous
Peer Reviewers Gemma Sicouri; Cerisse Gunasinghe
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • Chief Scientist Office, Scottish Government Health and Social Care Directorate
  • MRC Mental Health Data Pathfinder
  • Medical Research Council
  • Chief Scientist Office
  • MRC Human Genetics Unit
LATEST VERSION PUBLISHED 24 May 2022
https://doi.org/10.12688/wellcomeopenres.17325.2
Data Note metrics
Revised
RuralCovidLife: A new resource for the impact of the pandemic on rural Scotland.
[version 2; peer review: 2 approved]
Anna J Stevenson, Charlotte F Huggins, Alison Forbes, Jim Hume, Grant Fulton, Claire Thirlwall, Janet Miles, Chloe Fawns-Ritchie, Archie Campbell, Clifford Nangle, Rebecca Dawson, Rachel Edwards, Robin Flaig, Louise Hartley, Christie Levein, Daniel L McCartney, Ian J Deary, Caroline Hayward, Riccardo E Marioni, Andrew M McIntosh, Cathie Sudlow, David J Porteous
Peer Reviewers Holly Hope; Clifford Stevenson
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • Chief Scientist Office, Scottish Government Health and Social Care Directorate
  • Wellcome Trust - University of Edinburgh Institutional Strategic Support Fund
LATEST VERSION PUBLISHED 23 May 2022
https://doi.org/10.12688/wellcomeopenres.17322.2
Research Article metrics
Revised
The genetic and epigenetic profile of serum S100β in the Lothian Birth Cohort 1936 and its relationship to Alzheimer’s disease
[version 2; peer review: 2 approved]
Danni A Gadd, Robert I McGeachan, Robert F Hillary, Daniel L McCartney, Sarah E Harris, Roy A Sherwood, N Joan Abbott, Simon R Cox, Riccardo E Marioni
Peer Reviewers Nicholas W. Wood; Manu Sharma
  • Funders
  • Centre for Cognitive Ageing and Cognitive Epidemiology
  • Alzheimer’s Society major project grant
  • Alzheimer’s Research UK major project grant
  • Wellcome Trust PhD for clinicians, Edinburgh Clinical Academic Track for Veterinary Surgeons
  • Wellcome Trust 4-year PhD in Translational Neuroscience–training the next generation of basic neuroscientists to embrace clinical research
  • Medical Research Council
  • Age UK and NIH Grants
  • Medical Research Council and Biotechnology and Biological Sciences Research Council
  • Biotechnology and Biological Sciences Research Council
  • Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society
LATEST VERSION PUBLISHED 27 Jan 2022
https://doi.org/10.12688/wellcomeopenres.15538.2
Research Article metrics
Revised
Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments
[version 2; peer review: 2 approved]
Tina Habota, Anca-Larisa Sandu, Gordon D. Waiter, Christopher J. McNeil, J. Douglas Steele, Jennifer A. Macfarlane, Heather C. Whalley, Ruth Valentine, Dawn Younie, Nichola Crouch, Emma L. Hawkins, Yoriko Hirose, Liana Romaniuk, Keith Milburn, Gordon Buchan, Tessa Coupar, Mairi Stirling, Baljit Jagpal, Beverly MacLennan, Lucasz Priba, Mathew A. Harris, Jonathan D. Hafferty, Mark J. Adams, Archie I. Campbell, Donald J. MacIntyre, Alison Pattie, Lee Murphy, Rebecca M. Reynolds, Rebecca Elliot, Ian S. Penton-Voak, Marcus R. Munafò, Kathryn L. Evans, Jonathan R. Seckl, Joanna M. Wardlaw, Stephen M. Lawrie, Christopher S. Haley, David J. Porteous, Ian J. Deary, Alison D. Murray, Andrew M. McIntosh
Peer Reviewers Debbie A Lawlor; Helen Lavretsky
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • University of Edinburgh
  • Scottish Government Health and Social Care Directorate
  • Medical Research Council
  • Horizon 2020
LATEST VERSION PUBLISHED 16 Jul 2021
https://doi.org/10.12688/wellcomeopenres.16987.1
Data Note metrics
CovidLife: a resource to understand mental health, well-being and behaviour during the COVID-19 pandemic in the UK
[version 1; peer review: 2 approved]
Chloe Fawns-Ritchie, Drew M. Altschul, Archie Campbell, Charlotte Huggins, Clifford Nangle, Rebecca Dawson, Rachel Edwards, Robin Flaig, Louise Hartley, Christie Levein, Daniel L. McCartney, David Bell, Elaine Douglas, Ian J. Deary, Caroline Hayward, Riccardo E. Marioni, Andrew M. McIntosh, Cathie Sudlow, David J. Porteous
Peer Reviewers Margarita Panayiotou; Joel W Hughes
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • Scottish Government Health Directorates
  • Medical Research Council
PUBLISHED 07 Jul 2021
https://doi.org/10.12688/wellcomeopenres.16820.1
Research Article metrics
Socioeconomic position and mental health during the COVID-19 pandemic: a cross-sectional analysis of the CovidLife study
[version 1; peer review: 2 approved with reservations]
Miranda Pierre, Markéta Keller, Drew Altschul, Chloe Fawns-Ritchie, Louise Hartley, Clifford Nangle, Rachel Edwards, Rebecca Dawson, Archie Campbell, Robin Flaig, David J. Porteous
Peer Reviewers Anna Pearce; Yara J Toenders
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • British Academy
  • Chief Scientist Office, Scottish Government Health and Social Care Directorate
  • Medical Research Council
PUBLISHED 03 Jun 2021
https://doi.org/10.12688/wellcomeopenres.16458.2
Software Tool Article metrics
Revised
MethylDetectR: a software for methylation-based health profiling
[version 2; peer review: 2 approved]
Robert F. Hillary, Riccardo E. Marioni
Peer Reviewers Gemma Sharp; Charlotte Cecil
  • Funders
  • Centre for Cognitive Ageing and Cognitive Epidemiology
  • The University of Queensland
  • Scottish Funding Council
  • Chief Scientist Office of the Scottish Government Health Directorates
  • The University of Edinburgh
  • The Wellcome Trust Institutional Strategic Support Fund
  • Age UK
  • Wellcome
  • Medical Research Council
  • National Institutes of Health
  • Alzheimer’s Research UK
LATEST VERSION PUBLISHED 13 Apr 2021
https://doi.org/10.12688/wellcomeopenres.15651.2
Research Article metrics
Revised
Using a knowledge exchange event to assess study participants’ attitudes to research in a rapidly evolving research context
[version 2; peer review: 3 approved]
Iona Beange, Elizabeth J. Kirkham, Sue Fletcher-Watson, Matthew H. Iveson, Stephen M. Lawrie, G. David Batty, James P. Boardman, Ian J. Deary, Corri Black, David J. Porteous, Andrew M. McIntosh
Peer Reviewers Mhairi Stewart; Becky Hothersall; Justin Starren
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Horizon 2020
  • Theirworld
LATEST VERSION PUBLISHED 28 Aug 2020
https://doi.org/10.12688/wellcomeopenres.15354.2
Research Article metrics
Revised
Generation Scotland participant survey on data collection
[version 2; peer review: 2 approved]
Rachel Edwards, Archie Campbell, David Porteous
Peer Reviewers Elaine Douglas; Claire J. Steves
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • Chief Scientist Office, Scottish Government Health and Social Care Directorate
LATEST VERSION PUBLISHED 13 Dec 2019
https://doi.org/10.12688/wellcomeopenres.15136.1
Research Article metrics
Assessment of dried blood spots for DNA methylation profiling
[version 1; peer review: 2 approved]
Rosie M. Walker, Louise MacGillivray, Sarah McCafferty, Nicola Wrobel, Lee Murphy, Shona M. Kerr, Stewart W. Morris, Archie I. Campbell, Andrew M. McIntosh, David J. Porteous, Kathryn L. Evans
Peer Reviewers Jeffrey M. Craig; JiHoon Eric Joo
  • Funders
  • Wellcome Trust
  • Scottish Funding Council
  • Cross-Council Lifelong Health and Wellbeing Initiative
  • Medical Research Council
  • Chief Scientist Office
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 06 Mar 2019
https://doi.org/10.12688/wellcomeopenres.14576.2
Study Protocol metrics
Revised
DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain
[version 2; peer review: 2 approved]
Mathilde M.V. Pascal, Andreas C. Themistocleous, Ralf Baron, Andreas Binder, Didier Bouhassira, Geert Crombez, Nanna B. Finnerup, Janne Gierthmühlen, Yelena Granovsky, Leif Groop, Harry L. Hebert, Troels S. Jensen, Kristinn Johnsen, Mark I. McCarthy, Weihua Meng, Colin N.A. Palmer, Andrew S.C. Rice, Jordi Serra, Romà Solà, David Yarnitsky, Blair H. Smith, Nadine Attal, David L.H. Bennett
Peer Reviewers Simon Haroutounian; Miroslav Backonja
  • Funders
  • Wellcome Trust
  • Horizon 2020 Framework Programme
  • Novo Nordisk Fonden
LATEST VERSION PUBLISHED 01 Feb 2019
https://doi.org/10.12688/wellcomeopenres.13893.2
Research Article metrics
Revised
Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism
[version 2; peer review: 1 approved, 2 approved with reservations]
Toni-Kim Clarke, Yanni Zeng, Lauren Navrady, Charley Xia, Chris Haley, Archie I. Campbell, Pau Navarro, Carmen Amador, Mark J. Adams, David M. Howard, Aleix Soler, Caroline Hayward, Pippa A. Thomson, Blair H. Smith, Sandosh Padmanabhan, Lynne J. Hocking, Lynsey S. Hall, David J. Porteous, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ian J. Deary, Andrew M. McIntosh
Peer Reviewers Margaret Gatz; Lance Rappaport; Sarah Cohen-Woods
  • Funders
  • Wellcome Trust
  • Dr. Mortimer and Theresa Sackler Foundation
  • Scottish Funding Council
  • Scottish Government Health Directorates
  • Medical Research Council
  • Biotechnology and Biological Sciences Research Council
LATEST VERSION PUBLISHED 14 Jan 2019
https://doi.org/10.12688/wellcomeopenres.12583.3
Research Article metrics
Revised
Meta-analysis of exome array data identifies six novel genetic loci for lung function
[version 3; peer review: 2 approved]
Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove, Traci M. Bartz, Ma'en Obeidat, Michael A. Province, Wei Gao, Beenish Qaiser, David J. Porteous, Patricia A. Cassano, Tarunveer S. Ahluwalia, Niels Grarup, Jin Li, Elisabeth Altmaier, Jonathan Marten, Sarah E. Harris, Ani Manichaikul, Tess D. Pottinger, Ruifang Li-Gao, Allan Lind-Thomsen, Anubha Mahajan, Lies Lahousse, Medea Imboden, Alexander Teumer, Bram Prins, Leo-Pekka Lyytikäinen, Gudny Eiriksdottir, Nora Franceschini, Colleen M. Sitlani, Jennifer A. Brody, Yohan Bossé, Wim Timens, Aldi Kraja, Anu Loukola, Wenbo Tang, Yongmei Liu, Jette Bork-Jensen, Johanne M. Justesen, Allan Linneberg, Leslie A. Lange, Rajesh Rawal, Stefan Karrasch, Jennifer E. Huffman, Blair H. Smith, Gail Davies, Kristin M. Burkart, Josyf C. Mychaleckyj, Tobias N. Bonten, Stefan Enroth, Lars Lind, Guy G. Brusselle, Ashish Kumar, Beate Stubbe, Understanding Society Scientific Group, Mika Kähönen, Annah B. Wyss, Bruce M. Psaty, Susan R. Heckbert, Ke Hao, Taina Rantanen, Stephen B. Kritchevsky, Kurt Lohman, Tea Skaaby, Charlotta Pisinger, Torben Hansen, Holger Schulz, Ozren Polasek, Archie I. Campbell, John M. Starr, Stephen S. Rich, Dennis O. Mook-Kanamori, Åsa Johansson, Erik Ingelsson, André G. Uitterlinden, Stefan Weiss, Olli T. Raitakari, Vilmundur Gudnason, Kari E. North, Sina A. Gharib, Don D. Sin, Kent D. Taylor, George T. O'Connor, Jaakko Kaprio, Tamara B. Harris, Oluf Pederson, Henrik Vestergaard, James G. Wilson, Konstantin Strauch, Caroline Hayward, Shona M. Kerr, Ian J. Deary, R. Graham Barr, Renée de Mutsert, Ulf Gyllensten, Andrew P. Morris, M. Arfan Ikram, Nicole Probst-Hensch, Sven Gläser, Eleftheria Zeggini, Terho Lehtimäki, David P. Strachan, Josée Dupuis, Alanna C. Morrison, Ian P. Hall, Martin D. Tobin, Stephanie J. London
Peer Reviewers Rachel M. Freathy and Robin Beaumont; Lisa Strug and Naim Panjwani
  • Funders
  • Wellcome Trust
  • Economic and Social Research Council
  • Netherlands Organization for Scientific Research
  • National Heart, Lung, and Blood Institute
  • Swedish Research Council
  • National Institutes of Health
  • Dutch Science Organisation
  • National Institute on Aging
  • Academy of Finland
  • Ministry of Science, Education and Sports of the Republic of Croatia
  • U.S. Department of Health and Human Services
  • European Commission FP6
  • The Åke Wiberg foundation
  • National Institute of Environmental Health Sciences
  • National Center for Advancing Translational Sciences
  • National Center for Advancing Translation Studies
  • Scottish Funding Council
  • Netherlands Genomics Initiative/Netherlands Consortium for Healthy Aging
  • Scottish Government Health Directorates
  • National Institute of Nursing Research
  • Knut och Alice Wallenberg Foundation
  • National Institute of General Medical Sciences
  • Leids Universitair Medisch Centrum
  • Centre National de Génotypage
  • Swedish Society for Medical Research
  • Federal Ministry of Education and Research
  • National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center
  • Age UK
  • Swiss National Science Foundation
  • The Kjell och Märta Beijers Foundation
  • Medical Research Council
  • The Marcus Borgström Foundation
  • The Vleugels Foundation
  • Research Institute for Diseases in the Elderly
  • The Royal Society of Edinburgh
  • Federal State of Mecklenburg-West Pomerania
  • Swedish Heart-Lung Foundation
  • US Environmental Protection Agency
LATEST VERSION PUBLISHED 07 Aug 2018
https://doi.org/10.12688/wellcomeopenres.13854.1
Research Article metrics
Genetic and environmental contributions to psychological resilience and coping
[version 1; peer review: 2 approved]
Lauren B Navrady, Yanni Zeng, Toni-Kim Clarke, Mark J Adams, David M Howard, Ian J. Deary, Andrew M. McIntosh
Peer Reviewers Maria Antonietta Stazi; Margaret Gatz
  • Funders
  • Wellcome Trust
  • Medical Research Council
  • Scottish Government Health Department, Chief Scientist Office
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 15 Feb 2018
https://doi.org/10.12688/wellcomeopenres.12600.1
Data Note metrics
Electronic health record and genome-wide genetic data in Generation Scotland participants
[version 1; peer review: 2 approved, 1 approved with reservations]
Shona M. Kerr, Archie Campbell, Jonathan Marten, Veronique Vitart, Andrew M. McIntosh, David J. Porteous, Caroline Hayward
Peer Reviewers Sara J. Brown; Carol Brayne; Susan J. Lindsay
  • Funders
  • Wellcome Trust
  • Scottish Executive Health Department
  • Scottish Funding Council
  • Medical Research Council
PUBLISHED 18 Sep 2017
https://doi.org/10.12688/wellcomeopenres.12171.1
Research Article metrics
Negative/null result
Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank
[version 1; peer review: 2 approved]
David M. Howard, Mark J. Adams, Toni-Kim Clarke, Eleanor M. Wigmore, Yanni Zeng, Saskia P. Hagenaars, Donald M. Lyall, Pippa A. Thomson, Kathryn L. Evans, David J. Porteous, Reka Nagy, Caroline Hayward, Chris S. Haley, Blair H. Smith, Alison D. Murray, G. David Batty, Ian J. Deary, Andrew M. McIntosh
Peer Reviewers Antony Payton; Heiner Rindermann
  • Funders
  • Wellcome Trust
  • Scottish Government Health Directorate
  • China Scholarship Council
  • Scottish Funding Council
  • Dr. Mortimer and Theresa Sackler Foundation
  • Medical Research Council
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 10 Aug 2017
1-17 of 17 ARTICLES
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