Wellcome Trust/DBT India Alliance

Advisor: Dr Lolitika Mandal

Under the canopy of Biomedical Sciences, the gateway area Molecular, Cellular and Developmental Biology (MCDB) intends to focus on fundamental processes in cellular, molecular and developmental biology and how problems in these processes lead to the diseased condition. In addition to diverse experimental models, that includes mouse, zebrafish, C. elegans, Drosophila, etc, a range of protozoan and metazoan pathogens and cell line studies will be relevant to enrich this gateway. We will also extend our theme to encompass studies on cell cycle, chromosomes, gene expression, epigenetics and stem cell biology aiming to unravel the core processes and mechanisms that ensure normal development.

Advisor: Dr SP Arun

the objectivs of this gateway area are to promote dissemination of neuroscience research at all levels of organization, from molecules to mind. We especially encourage the publication of negative results that can help other researchers design better experiments and avoid duplicating effort.

Advisor: Dr Narendra Dixit

Computational techniques have assumed a place of importance in biomedical research today. The application of principles from the physical and the data sciences to the analysis of complex biological systems is creating new avenues of investigation and translation. The predictive power of mechanistic as well as data-driven models can help generate novel hypotheses, guide experimental design, and facilitate interpretation of experimental results, expediting discovery.

Advisor: Dr R Mahalakshmi

Solving the molecular details of biomolecule structure and function is indispensable to understanding their role in regulating homeostasis, and the occurrence of disease states. Presently, the research focus is to obtain a mechanistic insight of biomolecules - from single molecules to macromolecular complexes - in their near-native state using basic biochemistry, cutting-edge tools of structural biology, and innovative biophysical methods. This gateway area aims to showcase the latest high quality research discoveries in the areas of Biochemistry, Biophysics and Structural Biology.

Advisor: Dr Pallab Maulik

Clinical and public health research is a unique stream where researchers are in direct contact with patients or community and the impact of their research is directly relevant to people. Given this, it is of utmost importance that research outcomes generated through clinical and public health research are disseminated to the widest possible stakeholders to be widely known and offer others the opportunity confirm the findings. The learnings from one research can then be used effectively to generate newer evidence, and inform policy and practice.