KEMRI | Wellcome Trust
KEMRI | Wellcome Trust
Clinical Research
Research Article
metrics
Outborn Neonates in Nairobi’s Public Hospitals: Mortality Burden and Associated Risk Factors in a Retrospective Cohort Study
[version 1; peer review: 3 approved with reservations]
Peer Reviewers
Hassib Narchi;
Olufunke Bolaji;
Alexander G Stevenson
- Funder
- Wellcome Trust
Study Protocol
metrics
Revised
A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA)
[version 2; peer review: 3 approved]
Peer Reviewers
Stephen J Aston;
Matthias Briel and Christof Schönenberger;
Naveed Saleem
- Funder
- Wellcome Trust
Research Article
metrics
Revised
Examining the impact of implementing routine rotavirus vaccination on the number of paediatric admissions due to diarrhoea and dehydration in Kenyan hospitals: A study using interrupted time series analysis.
[version 2; peer review: 1 approved, 3 approved with reservations, 1 not approved]
Peer Reviewers
Mavuto Mukaka;
Dan Hungerford;
Khitam Muhsen;
Tayebeh Latifi;
Flavia Kaduni Bawa
- Funder
- Wellcome Trust
Study Protocol
metrics
Revised
SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Mei Li;
Bruno Mmbando;
Joerg J. Moehrle
- Funder
- Wellcome
Study Protocol
metrics
A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)
[version 1; peer review: 2 approved]
Peer Reviewers
Alexuse Saidi;
Collins Ouma and Dr. Bernard Guyah
- Funder
- Wellcome Trust
Study Protocol
metrics
Revised
Mortality among non-severely under nourished children with pneumonia globally: protocol for a systematic review and meta-analysis
[version 2; peer review: 3 approved]
Peer Reviewers
Rouzha Pancheva;
Felix Bongomin;
Olivier Marcy
- Funders
- European and Developing Countries Clinical Trials Partnership
- Wellcome
- UK Joint Global Health Trials scheme: Medical Research Council, Department for International Development Wellcome Trust
Study Protocol
metrics
Revised
Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol
[version 2; peer review: 2 approved]
Peer Reviewers
C. Louise Thwaites;
Roberta Petrucci
- Funders
- Wellcome Trust
- Medical Research Council
Research Article
metrics
Clinical trial
Safety and immunogenicity of varied doses of R21/Matrix-M™ vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya
[version 1; peer review: 2 approved]
Peer Reviewers
George Ayodo;
Irene S Soares
- Funders
- Horizon 2020 Framework Programme
- Wellcome
Research Article
metrics
Revised
Patterns of neurobehavioral functioning in school-aged survivors of neonatal jaundice and hypoxic-ischemic encephalopathy in Kilifi, Kenya: A cross-sectional study
[version 3; peer review: 1 approved, 1 approved with reservations, 5 not approved]
Peer Reviewers
Bolajoko O. Olusanya;
Deirdre Murray;
Tina M. Slusher;
Brigitte Vollmer;
Raj Prakash;
Alan Horn and Shakti Pillay;
Lakshmi Nagarajan
- Funders
- Wellcome Trust
- African Academy of Sciences
- New Partnership for Africa's Development
- Department for International Development, UK Government
Research Article
metrics
Revised
Using self-supervised feature learning to improve the use of pulse oximeter signals to predict paediatric hospitalization
[version 2; peer review: 2 approved]
Peer Reviewers
Ciira wa Maina;
Shaun Davidson
- Funders
- Wellcome Trust
- DELTAS Africa Initiative
- Initiative to Develop African Research Leaders (IDeAL)
Research Article
metrics
Revised
Development of a legume-enriched feed for treatment of severe acute malnutrition
[version 2; peer review: 2 approved]
Peer Reviewers
Sumathi Swaminathan;
Paluku Bahwere and Peter Akomo
- Funders
- Wellcome Trust
- Rosetrees Trust
- National Institute for Health Research
- Yuhan
- Medical Research Council
- Imperial College London
- AstraZeneca
- Royal Marsden NHS Foundation Trust
- Engineering and Physical Sciences Research Council
Study Protocol
metrics
Clinical trial
Revised
Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial
[version 2; peer review: 2 approved]
Peer Reviewers
Stephen J. Rogerson;
Nworgu Confidence ogechi
- Funders
- Wellcome Trust
- National Institute for Health Research
- Medical Research Council
- Foreign, Commonwealth and Development Office
- Department of Health and Social Care
Open Letter
metrics
Revised
Maintaining laboratory quality assurance and safety in a pandemic: Experiences from the KEMRI-Wellcome Trust Research Programme laboratory’s COVID-19 response
[version 2; peer review: 2 approved]
Peer Reviewers
Talkmore Maruta;
Angela Amayo
- Funders
- Wellcome Trust
- Wellcome Trust Intermediate Fellowship
- European and Developing Countries Clinical Trials Partnership (EDCTP)
- International Drug Purchasing Facility
- Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)
- African Academy of Sciences DELTAS Africa Initiative
- Program for Appropriate Technology in Health (PATH)
Study Protocol
metrics
TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults)
[version 1; peer review: 3 approved]
Peer Reviewers
Eric J. Lavonas;
Matthew Lewin;
Matthew Coldiron
- Funders
- Cures Within Reach
- Wellcome
- Research England
Method Article
metrics
Revised
An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams
[version 2; peer review: 2 approved]
Peer Reviewers
Davis Nwakanma;
Esther Omuseni and John Waitumbi
- Funders
- Wellcome Trust
- DELTAS Africa Initiative
- PATH
- National Institute for Health Research
- Department for International Development, UK Government
Study Protocol
metrics
Revised
Children’s Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial
[version 2; peer review: 2 approved]
Peer Reviewers
Carina King;
Jamie Rylance
- Funders
- Wellcome Trust
- European and Developing Countries Clinical Trials Partnership
- Department for International Development
- Medical Research Council
Research Article
metrics
Revised
Mortality during and following hospital admission among school-aged children: a cohort study
[version 2; peer review: 3 approved]
Peer Reviewers
Bruno Masquelier;
Duncan Hau;
Matthew Wiens
- Funders
- Wellcome Trust
- World Health Organization
- TDR
- Department for International Development, UK Government
- Medical Research Council
- Gates Foundation
Research Article
metrics
Revised
Plasma calprotectin as a biomarker of mortality at antiretroviral treatment initiation in advanced HIV – pilot study
[version 2; peer review: 2 approved]
Peer Reviewers
Rachel A. Silverman;
Rupak Shivakoti
- Funders
- Wellcome Trust
- African Academy of Sciences
- New Partnership for Africa's Development
- Department for International Development, UK Government
- Medical Research Council
- PENTA Foundation
- Gates Foundation
Research Article
metrics
Revised
Characterising demographics, knowledge, practices and clinical care among patients attending sickle cell disease clinics in Eastern Uganda
[version 2; peer review: 2 approved]
Peer Reviewers
Simon Dyson;
Baba Inusa
- Funder
- Wellcome Trust
Research Article
metrics
Revised
Rectal gonorrhoea and chlamydia among men who have sex with men in coastal Kenya
[version 4; peer review: 2 approved]
Peer Reviewers
Michael W. Ross;
Nicola Low
- Funders
- Wellcome Trust
- International AIDS Vaccine Initiative
- African Academy of Sciences
- New Partnership for Africa's Development
- Department for International Development, UK Government
- National Institutes of Health
- Sub-Saharan African Network for TB/HIV Research Excellence
- Robert W. Anderson Endowed Professorship