KEMRI | Wellcome Trust

KEMRI | Wellcome Trust

Genomics and infectious disease transmission

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1-20 of 38 ARTICLES
https://doi.org/10.12688/wellcomeopenres.25620.2
Open Letter metrics
Revised
Cross- Wellcome Africa Asian Programmes (AAPs) Acceleration of Genomics for Escalating infectious Diseases, (CAGED) Consortium
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Rakesh K Mishra; Marina Igorova Reyne; Gerald Mboowa
  • Funder
  • Wellcome
LATEST VERSION PUBLISHED 05 Jun 2026
https://doi.org/10.12688/wellcomeopenres.25865.1
Research Article metrics
Molecular Epidemiology of Human Metapneumovirus in Kilifi, Coastal Kenya, 2016-2017 and 2021-2024
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Stephanie Goya; Carla della Ventura
  • Funders
  • Wellcome
  • National Institute of Health and Care Research
PUBLISHED 12 Feb 2026
https://doi.org/10.12688/wellcomeopenres.17908.4
Research Article metrics
Revised
Surveillance of respiratory viruses at health facilities from across Kenya, 2014
[version 4; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers David P Moore; W. Abdullah Brooks; Rino Rappuoli
  • Funders
  • Wellcome Trust
  • U.S. Centers for Disease Control and Prevention
LATEST VERSION PUBLISHED 11 Dec 2025
https://doi.org/10.12688/wellcomeopenres.24183.2
Research Note metrics
Revised
Coxsackievirus A24 variant whole genome sequencing from clinical samples using a three overlapping amplicons strategy
[version 2; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers Peter van Heusden; Sanjay Tikute; Charles Patrick Mcclure; Jake D'Addiego
  • Funders
  • Wellcome Trust
  • Rockefeller Foundation
  • National Institute of Health and Care Research
LATEST VERSION PUBLISHED 06 Oct 2025
https://doi.org/10.12688/wellcomeopenres.24303.1
Research Article metrics
Contexts, Facilitators, and Barriers to Integrating Portable Genomics for Outbreak Response in Coastal Kenya: A Qualitative Analysis of Participatory Stakeholder Discussions
[version 1; peer review: 2 approved with reservations]
Peer Reviewers JAIME BRISENO-RAMIREZ; Alicia Arnott
  • Funders
  • Wellcome Trust
  • Department of Health and Social Care (DHSC), UK
PUBLISHED 19 Sep 2025
https://doi.org/10.12688/wellcomeopenres.20240.2
Research Article metrics
Revised
Comparative performance of the InBios SCoV-2 DetectTM IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations
[version 2; peer review: 2 approved]
Peer Reviewers Samira Bührer-Sékula and Matheus Bernardes Torres; Abhinay Gontu
  • Funders
  • Wellcome Trust
  • Gates Foundation
LATEST VERSION PUBLISHED 28 Jul 2025
https://doi.org/10.12688/wellcomeopenres.24091.1
Research Article metrics
Metagenomic exploration of antimicrobial resistance genes in marine bacteria ecosystem
[version 1; peer review: 1 approved with reservations, 1 not approved]
Peer Reviewers Adenike Adenaya; Alan Elena
  • Funder
  • This work was supported by Science for Africa Foundation to the Developing Excellence in Leadership, Training, and Science in Africa (DELTAS Africa) program [DEL-22-012] with support from Wellcome Trust and the UK Foreign, Commonwealth & Development Office and is part of the EDCPT2 programme supported by the European Union.
PUBLISHED 19 May 2025
https://doi.org/10.12688/wellcomeopenres.19414.2
Research Article metrics
Revised
Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study
[version 2; peer review: 2 approved]
Peer Reviewers Eleonora Nicolai; Flaminia Tomassetti
  • Funders
  • Wellcome Trust
  • European and Developing Countries Clinical Trials Partnership
  • Medical Research Council
  • The Developing Excellence in Leadership, Training, and Science in Africa
LATEST VERSION PUBLISHED 02 Dec 2024
https://doi.org/10.12688/wellcomeopenres.17736.4
Research Article metrics
Revised
Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial
[version 4; peer review: 2 approved, 2 approved with reservations]
Peer Reviewers Ian M. Hastings; Toshihiro Mita; Eniyou Cheryll Oriero; Aurel Holzschuh
  • Funders
  • Wellcome Trust
  • Developing Excellence in Leadership, Training and Science (DELTAS) Africa Initiative
  • National Institutes of Health
LATEST VERSION PUBLISHED 14 Mar 2024
https://doi.org/10.12688/wellcomeopenres.18868.2
Research Article metrics
Revised
Metagenomic analysis of coastal Kenya female Aedes aegypti mosquito RNA metaviromes reveal presence of diverse insect specific viruses
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Jandouwe Villinger; Lícia Natal Fernandes
  • Funders
  • Wellcome Trust
  • Medical Research Council, Wellcome Trust, and Newton Fund
LATEST VERSION PUBLISHED 16 Aug 2023
https://doi.org/10.12688/wellcomeopenres.18908.1
Research Article metrics
SARS-CoV-2 Omicron variant of concern in the Seychelles: Introduction and spread
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Jordan Douglas; Steven C. Holland
  • Funders
  • Wellcome Trust
  • National Institute for Health Research (NIHR)
PUBLISHED 24 Feb 2023
https://doi.org/10.12688/wellcomeopenres.18700.1
Research Article metrics
Detection of a SARS-CoV-2 Beta-like variant in coastal Kenya after more than a year of disappearance
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Zahra Hasan; Kathleen Subramoney
  • Funders
  • UK Department of Health and Social Care
  • Wellcome
  • National Institute for Health and Care Research
PUBLISHED 20 Jan 2023
https://doi.org/10.12688/wellcomeopenres.16748.3
Research Article metrics
Revised
Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Mark Kimathi; Amy Wesolowski; Benjamin J. Cowling
  • Funders
  • Wellcome Trust
  • National Institute for Health Research
  • Medical Research Council
  • Foreign, Commonwealth and Development Office
LATEST VERSION PUBLISHED 22 Sep 2022
https://doi.org/10.12688/wellcomeopenres.17636.2
Research Article metrics
Revised
Efficiency of transplacental transfer of respiratory syncytial virus (RSV) specific antibodies among pregnant women in Kenya
[version 2; peer review: 2 approved]
Peer Reviewers Kondwani Charles Jambo; Beate Kampmann
  • Funders
  • Centers for Disease Control and Prevention
  • Wellcome
  • Pfizer
LATEST VERSION PUBLISHED 01 Apr 2022
https://doi.org/10.12688/wellcomeopenres.17661.1
Research Article metrics
Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya
[version 1; peer review: 2 approved]
Peer Reviewers Olusola Anuoluwapo Akanbi; Maryam Meskini
  • Funders
  • African Academy of Sciences
  • USAID
  • EDCTP
  • GAVI
  • Oak Foundation
  • UNITAID
  • International AIDS Vaccine Initiative
  • Government of the United Kingdom
  • Wellcome
  • National Institute for Health Research
  • New Partnership for Africa's Development
  • Gates Foundation
PUBLISHED 23 Feb 2022
https://doi.org/10.12688/wellcomeopenres.17656.1
Research Article metrics
Spatio-temporal distribution of antimalarial drug resistant gene mutations in a Plasmodium falciparum parasite population from Kilifi, Kenya: A 25-year retrospective study
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Fatima Nogueira; Melissa Conrad
  • Funder
  • Wellcome Trust
PUBLISHED 08 Feb 2022
https://doi.org/10.12688/wellcomeopenres.16756.1
Research Article metrics
Enrichment approach for unbiased sequencing of respiratory syncytial virus directly from clinical samples
[version 1; peer review: 3 approved, 1 approved with reservations]
Peer Reviewers Martin M. Nyaga and Milton Mogotsi; Gerald Mboowa; Tanya Golubchik; Christopher Illingworth
  • Funders
  • Wellcome Trust
  • DELTAS Africa Initiative
  • National Institutes of Health
PUBLISHED 07 May 2021
https://doi.org/10.12688/wellcomeopenres.16131.2
Research Article metrics
Revised
Impact of Plasmodium falciparum small-sized extracellular vesicles on host peripheral blood mononuclear cells
[version 2; peer review: 1 approved, 2 not approved]
Peer Reviewers Smart Ikechukwu Mbagwu; Carmenza Spadafora; Valery Combes and Ricardo Correa
  • Funders
  • Wellcome Trust
  • African Academy of Sciences
  • Alliance for Accelerating Excellence in Science in Africa
LATEST VERSION PUBLISHED 13 Apr 2021
https://doi.org/10.12688/wellcomeopenres.16330.2
Research Article metrics
Revised
Systemic inflammation is negatively associated with early post discharge growth following acute illness among severely malnourished children - a pilot study
[version 2; peer review: 2 approved]
Peer Reviewers Sana Syed and Lubaina Ehsan; Keith P. West
  • Funders
  • Wellcome Trust
  • Department for International Development, UK Government
  • Medical Research Council
  • Gates Foundation
LATEST VERSION PUBLISHED 16 Mar 2021
https://doi.org/10.12688/wellcomeopenres.16113.2
Research Article metrics
Revised
Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast
[version 2; peer review: 3 approved]
Peer Reviewers Ernest Wandera Apondi and Jesse Gitaka; Kenny Voon; James A Hay
  • Funders
  • Wellcome Trust
  • African Academy of Sciences
  • Alliance for Accelerating Excellence in Science in Africa
  • New Partnership for Africa's Development
  • National Institute for Health Research
  • Department for International Development, UK Government
LATEST VERSION PUBLISHED 03 Feb 2021
1-20 of 38 ARTICLES
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